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1.
Front Plant Sci ; 10: 1404, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31737019

RESUMO

Weeds in agricultural farms are aggressive growers which compete for nutrition and other resources with the crop and reduce production. The increasing use of chemicals to control them has inadvertent consequences to the human health and the environment. In this work, a novel neural network training method combining semantic graphics for data annotation and an advanced encoder-decoder network for (a) automatic crop line detection and (b) weed (wild millet) detection in paddy fields is proposed. The detected crop lines act as a guiding line for an autonomous weeding robot for inter-row weeding, whereas the detection of weeds enables autonomous intra-row weeding. The proposed data annotation method, semantic graphics, is intuitive, and the desired targets can be annotated easily with minimal labor. Also, the proposed "extended skip network" is an improved deep convolutional encoder-decoder neural network for efficient learning of semantic graphics. Quantitative evaluations of the proposed method demonstrated an increment of 6.29% and 6.14% in mean intersection over union (mIoU), over the baseline network on the task of paddy line detection and wild millet detection, respectively. The proposed method also leads to a 3.56% increment in mIoU and a significantly higher recall compared to a popular bounding box-based object detection approach on the task of wild-millet detection.

2.
Int J Mol Sci ; 20(7)2019 Apr 08.
Artigo em Inglês | MEDLINE | ID: mdl-30965553

RESUMO

Cell cytotoxicity assays, such as cell viability and lactate dehydrogenase (LDH) activity assays, play an important role in toxicological studies of pharmaceutical compounds. However, precise modeling for cytotoxicity studies is essential for successful drug discovery. The aim of our study was to develop a computational modeling that is capable of performing precise prediction, processing, and data representation of cell cytotoxicity. For this, we investigated protective effect of quercetin against various mycotoxins (MTXs), including citrinin (CTN), patulin (PAT), and zearalenol (ZEAR) in four different human cancer cell lines (HeLa, PC-3, Hep G2, and SK-N-MC) in vitro. In addition, the protective effect of quercetin (QCT) against various MTXs was verified via modeling of their nonlinear protective functions using artificial neural networks. The protective model of QCT is built precisely via learning of sparsely measured experimental data by the artificial neural networks (ANNs). The neuromodel revealed that QCT pretreatment at doses of 7.5 to 20 µg/mL significantly attenuated MTX-induced alteration of the cell viability and the LDH activity on HeLa, PC-3, Hep G2, and SK-N-MC cell lines. It has shown that the neuromodel can be used to predict the protective effect of QCT against MTX-induced cytotoxicity for the measurement of percentage (%) of inhibition, cell viability, and LDH activity of MTXs.


Assuntos
Sobrevivência Celular/efeitos dos fármacos , Micotoxinas/farmacologia , Quercetina/farmacologia , Citrinina/farmacologia , Ativação Enzimática/efeitos dos fármacos , Fibroblastos/citologia , Fibroblastos/efeitos dos fármacos , Células HeLa , Células Hep G2 , Humanos , L-Lactato Desidrogenase/metabolismo , Células PC-3 , Patulina/farmacologia , Zeranol/análogos & derivados , Zeranol/farmacologia
3.
IEEE Trans Neural Netw Learn Syst ; 30(11): 3458-3470, 2019 11.
Artigo em Inglês | MEDLINE | ID: mdl-30762570

RESUMO

In this paper, a memristive artificial neural circuit imitating the excitatory chemical synaptic transmission of biological synapse is designed. The proposed memristor-based neural circuit exhibits synaptic plasticity, one of the important neurochemical foundations for learning and memory, which is demonstrated via the efficient imitation of short-term facilitation and long-term potentiation. Moreover, the memristive artificial circuit also mimics the distinct biological attributes of strong stimulation and deficient synthesis of neurotransmitters. The proposed artificial neural model is designed in SPICE, and the biological functionalities are demonstrated via various simulations. The simulation results obtained with the proposed artificial synapse are similar to the biological features of chemical synaptic transmission and synaptic plasticity.


Assuntos
Comportamento Imitativo , Redes Neurais de Computação , Plasticidade Neuronal , Transmissão Sináptica , Humanos , Comportamento Imitativo/fisiologia , Plasticidade Neuronal/fisiologia , Transmissão Sináptica/fisiologia
4.
Sensors (Basel) ; 18(1)2018 Jan 10.
Artigo em Inglês | MEDLINE | ID: mdl-29320467

RESUMO

This paper presents a vision sensor-based solution to the challenging problem of detecting and following trails in highly unstructured natural environments like forests, rural areas and mountains, using a combination of a deep neural network and dynamic programming. The deep neural network (DNN) concept has recently emerged as a very effective tool for processing vision sensor signals. A patch-based DNN is trained with supervised data to classify fixed-size image patches into "trail" and "non-trail" categories, and reshaped to a fully convolutional architecture to produce trail segmentation map for arbitrary-sized input images. As trail and non-trail patches do not exhibit clearly defined shapes or forms, the patch-based classifier is prone to misclassification, and produces sub-optimal trail segmentation maps. Dynamic programming is introduced to find an optimal trail on the sub-optimal DNN output map. Experimental results showing accurate trail detection for real-world trail datasets captured with a head mounted vision system are presented.

5.
Sensors (Basel) ; 17(1)2016 Dec 23.
Artigo em Inglês | MEDLINE | ID: mdl-28025566

RESUMO

A hybrid learning method of a software-based backpropagation learning and a hardware-based RWC learning is proposed for the development of circuit-based neural networks. The backpropagation is known as one of the most efficient learning algorithms. A weak point is that its hardware implementation is extremely difficult. The RWC algorithm, which is very easy to implement with respect to its hardware circuits, takes too many iterations for learning. The proposed learning algorithm is a hybrid one of these two. The main learning is performed with a software version of the BP algorithm, firstly, and then, learned weights are transplanted on a hardware version of a neural circuit. At the time of the weight transplantation, a significant amount of output error would occur due to the characteristic difference between the software and the hardware. In the proposed method, such error is reduced via a complementary learning of the RWC algorithm, which is implemented in a simple hardware. The usefulness of the proposed hybrid learning system is verified via simulations upon several classical learning problems.

6.
IEEE Trans Neural Netw Learn Syst ; 23(9): 1426-35, 2012 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-24807926

RESUMO

Analog hardware architecture of a memristor bridge synapse-based multilayer neural network and its learning scheme is proposed. The use of memristor bridge synapse in the proposed architecture solves one of the major problems, regarding nonvolatile weight storage in analog neural network implementations. To compensate for the spatial nonuniformity and nonideal response of the memristor bridge synapse, a modified chip-in-the-loop learning scheme suitable for the proposed neural network architecture is also proposed. In the proposed method, the initial learning is conducted in software, and the behavior of the software-trained network is learned by the hardware network by learning each of the single-layered neurons of the network independently. The forward calculation of the single-layered neuron learning is implemented on circuit hardware, and followed by a weight updating phase assisted by a host computer. Unlike conventional chip-in-the-loop learning, the need for the readout of synaptic weights for calculating weight updates in each epoch is eliminated by virtue of the memristor bridge synapse and the proposed learning scheme. The hardware architecture along with the successful implementation of proposed learning on a three-bit parity network, and on a car detection network is also presented.


Assuntos
Algoritmos , Biomimética/instrumentação , Redes Neurais de Computação , Processamento de Sinais Assistido por Computador/instrumentação , Sinapses , Desenho Assistido por Computador , Impedância Elétrica , Desenho de Equipamento , Análise de Falha de Equipamento
7.
Sensors (Basel) ; 11(4): 4372-84, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-22163852

RESUMO

This paper proposes an extension of the weak classifiers derived from the Haar-like features for their use in the Viola-Jones object detection system. These weak classifiers differ from the traditional single threshold ones, in that no specific threshold is needed and these classifiers give a more general solution to the non-trivial task of finding thresholds for the Haar-like features. The proposed quadratic discriminant analysis based extension prominently improves the ability of the weak classifiers to discriminate objects and non-objects. The proposed weak classifiers were evaluated by boosting a single stage classifier to detect rear of car. The experiments demonstrate that the object detector based on the proposed weak classifiers yields higher classification performance with less number of weak classifiers than the detector built with traditional single threshold weak classifiers.


Assuntos
Análise Discriminante , Veículos Automotores , Reconhecimento Automatizado de Padrão , Algoritmos , Teorema de Bayes , Humanos
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